General Cell Based Assays
Cayman Chemical Methyltrnsferase asy AdoHc 1ea
An ago-PAM of GLP-1R induces calcium mobilization in 9-3-H cells expressing human GLP-1R (EC50 1.3 UM) enhances GLP-1- exenatide- or liraglutide-induced calcium mobilization in the same cells (EC50s 1.8 8.4 and 30 UM respectively) potentiates exenatide-induced insulin secretion in primary mouse pancreatic islets at 30 UM reverses haloperidol-induced catalepsy in a rat model of Parkinson’s disease motor symptoms at 30 mg/kg
Cayman Chemical CelBased asy CyclohexImId 50uL
A peptide MC1R antagonist (IC50 17 nM) selectively binds to MC1R over MC3R and MC5R (IC50s 3900 and 1000 nM respectively) as well as MC4R at 10 UM increases the latency to tail withdrawal in the tail-flick test in female but not male mice in a model of opioid-induced hyperalgesia at 7.5 UG/animal i.c.v. reduces protein levels of merlin in the cortex reduces the number of surviving neurons in the cortex and hippocampal CA2 region and increases the number of apoptotic cells in the cortex in rats 24 hours after injury in a model of controlled cortical impact-induced TBI at 1 nmol/animal i.c.v.
Eurofins Discoverx AssayComplete Freezing Reagent F1, 2 x 50. (92-5101FR)
AssayComplete Freezing Reagent F1 is an optimized freezing reagent for cryopreservation of Eurofins DiscoverX cell lines. This reagent ensures optimal cell viability and assay performance upon thawing. This product is provided as 2 bottles of 50 mL reagent each. Please refer to cell line specific datasheet to determine the recommended freezing reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter Mouse EDNRA β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse EDNRA β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mouse EDNRA (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human TACR3 Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human TACR3 Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure TACR3 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CHRM2 Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CHRM2 Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CHRM2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human NPFFR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human NPFFR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NPFFR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR23 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR23 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR23 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human NMU1R Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human NMU1R Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure NMU1R (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CXCL11 (CXCR3) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CXCL11 (CXCR3) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CXCR3 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCL25 (CCR9) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CCL25 (CCR9) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR9 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.